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ADAMTS PROTEINS
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DeCS
Descriptor
English
:
ADAMTS Proteins
Descriptor
Spanish
:
Proteínas ADAMTS
Descriptor
Portuguese
:
Proteínas ADAMTS
Synonyms
English
:
A Disintegrin And Metalloproteinase With Thrombospondin Motifs Proteins
ADAMTS Proteases
ADAMTS-Like Proteins
ADAMTSL Proteins
Adam Metallopeptidases With Thrombospondin Type 1 Motif Proteins
ADAMTS Like Proteins
Tree Number:
D08.811.277.656.675.374.102.500
D09.400.430.500.500
D12.776.395.033.500
D12.776.860.300.085
Definition
English
:
A subfamily of ADAM proteases that are distinguished by the presence of one or more
THROMBOSPONDIN
type-1 repeats (TSRs). These are three-strand motifs that contain characteristic
TRYPTOPHAN
,
ARGININE
, and
CYSTEINE
residues respectively. In contrast to
ADAM proteins
, which reside on CELL
MEMBRANES
, ADAMTS proteases are secreted and function in the
EXTRACELLULAR MATRIX.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56485
Unique Identifier:
D000071096
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS